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Products for use in the clinical diagnosis of viral infections, including SARS-CoV-2, the virus that causes COVID-19, by simultaneously measuring multiple analytes from a single sample.
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The Meso Scale Discovery V-PLEX Mouse IL-27p28/IL-30 Kit is an electrochemiluminescent immunoassay for the quantitative measurement of IL-27p28 and IL-30 in mouse serum plasma and cell culture supernatants The assay uses MSD s proprietary V-PLEX technology is sensitive reproducible and requires a low sample volume of 25 L The kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with an electrochemiluminescent compound and calibrator solutions for generating standard curves The assay has a typical lower limit of detection of 0 04 pg/mL for IL-27p28 and 0 03 pg/mL for IL-30
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The Meso Scale Discovery Phospho (Ser/Thr) Akt 1/2/3 Assay Kit detects Akt proteins phosphorylated at serine and threonine in cell and tissue lysates This electrochemiluminescent assay uses MSD s SULFO-TAG labels and multi-array plate technology for rapid sensitive measurement of Akt phosphorylation with 1-2 g of protein per well It includes a 96-well plate with capture antibodies for Ser473 Thr308 and pan-Akt plus detection antibodies calibrator and solutions This kit enables high-throughput profiling of Akt phosphorylation in cancer diabetes neurodegeneration and immune disorders
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The Mesoscale K15436U-4 is a 4-channel 16-bit 250 kS/s simultaneous sampling data acquisition module It has 4 analog voltage input channels with programmable gain amplifiers anti-aliasing filters and 16-bit ADCs The input voltage range is 10 V with software-selectable gains of 1 2 4 8 It has a USB interface and is compatible with Windows Linux and Mac operating systems The module is bus-powered and compact in size Key features include 250 kS/s sampling rate 16-bit resolution 4 analog input channels programmable gains anti-aliasing filters USB interface and cross-platform software support
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The Meso Scale Discovery COVID-19 Respiratory Panel 1 IgG Assay Kit is an immunoassay that detects IgG antibodies to SARS-CoV-2 in human serum and plasma This qualitative assay uses MSD s electrochemiluminescence detection technology and provides results in under 5 hours The kit includes a 96-well plate coated with recombinant SARS-CoV-2 antigen detection antibody wash buffer read buffer calibrators and controls This assay aids in identifying individuals with an adaptive immune response to SARS-CoV-2 indicating recent or prior infection
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The Meso Scale Discovery V-PLEX SARS-CoV-2 Panel 2 (ACE2) Kit is a multiplex immunoassay that detects antibodies to SARS-CoV-2 in human serum and plasma It includes antigens for the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and the ACE2 protein The assay has high sensitivity and specificity for detecting antibodies that block binding between the RBD and ACE2 which may have neutralizing activity against SARS-CoV-2 Results are obtained in just a few hours using an electrochemiluminescent detection method on Meso Scale Discovery s instrumentation platforms The kit includes reagents for 96 tests when used on MSD s SECTOR Imager 6000
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The Meso Scale Discovery V-PLEX Plus Human ProInflam Panel II 4-plex is a kit for measuring 4 human proinflammatory biomarkers (IFN- IL-1 IL-6 and TNF- ) in serum plasma and cell culture supernatants using electrochemiluminescence detection technology The kit includes a 4-spot MULTI-ARRAY 96-well plate coated with capture antibodies detection antibodies calibrators diluent read buffer wash buffer and plate seals The assay has a typical sensitivity of 0 3-0 8 pg/mL and a 3 5 hour total assay time This multiplex immunoassay allows simultaneous quantification of multiple biomarkers from a single small sample volume
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The Meso Scale Discovery V-PLEX SARS-CoV-2 Panel 2 IgG Kit is an immunoassay that quantitatively measures IgG antibodies to SARS-CoV-2 in human serum and plasma It uses electrochemiluminescence detection technology and provides high sensitivity specificity and reproducibility The kit includes a 96-well plate coated with SARS-CoV-2 spike protein S1 and receptor binding domain antigens detection antibodies calibrators controls wash buffer read buffer and plate seals Results are reported in arbitrary units per milliliter and the assay has a run time of approximately 3 hours This product helps monitor immune response to SARS-CoV-2
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The Meso Scale Discovery V-PLEX SARS-CoV-2 Panel 1 Mouse IgM Kit is an electrochemiluminescent immunoassay for the qualitative detection of IgM antibodies to SARS-CoV-2 in serum and plasma from mice exposed to SARS-CoV-2 or a vaccine This assay uses a V-PLEX Mouse Immunoglobulin Panel 1 Plate coated with SARS-CoV-2 spike protein subunit 1 and nucleocapsid protein Results are obtained in under 3 hours using an MSD instrument This kit includes a plate diluent calibrator and controls to run the assay
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The Mesoscale K15693U-4 is a 4-channel 15kV 693uA high voltage power supply It provides up to 15kV at 693uA per channel with ripple noise less than 0 01% 500uVrms It has 4 independent high voltage outputs with remote voltage and current readback The K15693U-4 can be controlled via the front panel or remotely via Ethernet USB RS-232 or analog interfaces Safety features include arc detection overvoltage protection and overcurrent protection This compact 1U rackmount high voltage power supply is suitable for biasing MEMS devices vacuum electronics photomultipliers and other applications requiring stable low noise high voltage
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The Mesoscale K15695U-2 is a high-performance thermoelectric module for cooling heating and temperature control It features 127 Bismuth Telluride thermocouples between ceramic substrates With a max operating temperature of 200 C it offers a heat pumping capacity of 15 2W at a hot side of 50 C and cold side of 25 C Key features include a compact size of 40 x 40 x 3 4mm no moving parts for quiet operation and RoHS compliance Suitable for scientific instruments photonics laser systems and food cooling
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The Mesoscale K15373U-4 is a 4-channel 16-bit 250 kS/s simultaneous sampling data acquisition module It has 4 analog voltage input channels with programmable gain amplifiers anti-aliasing filters and 16-bit ADCs The input voltage range is 10 V with software-selectable gains of 1 2 4 8 It has a USB interface and is compatible with Windows Linux and Mac operating systems The module is bus-powered and compact in size Key features include 250 kS/s sampling rate 16-bit resolution 4 analog input channels programmable gains anti-aliasing filters USB interface and cross-platform software
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Meso Scale Discovery offers a variety of assay kits that enable detection of biomarkers immunogenicity and pharmacodynamic readouts using electrochemiluminescence technology Their assay kits are available for cytokines chemokines growth factors immunogenicity and pharmacodynamic biomarkers The kits provide high sensitivity broad dynamic range and low sample consumption They are compatible with a variety of sample types including serum plasma cell culture supernatants and more The assay kits are available in multiple- or single-plex formats
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The Meso Scale Diagnostics COVID-19 Coronavirus Panel 2 IgG is an in vitro diagnostic test kit that detects IgG antibodies to SARS-CoV-2 in human serum and plasma It uses electrochemiluminescence technology on Meso Scale Diagnostics proprietary MULTI-ARRAY platform The test kit includes a 96-well plate coated with SARS-CoV-2 antigens detection antibodies calibrators and controls It has 99 6% PPA and 99 6% NPA versus PCR and takes under 3 hours to run The test is CE marked and available for in vitro diagnostic use in countries recognizing the CE mark
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